Researchers develop method to program self assembling synthetic triple helices

Phys.org Chemistry reported that researchers at the University of Jyväskylä in Finland have developed a strategy for programming synthetic molecules. The process enables these molecules to self-assemble into precisely defined three-dimensional structures, specifically triple helices. [1]

The research team developed a control method to direct how the synthetic units arrange themselves. Phys.org Chemistry reported that this advance allows scientists to mimic the complex molecular organization found in biological systems, which may assist in creating advanced functional materials. [1]

Molecular machines are discrete assemblies of molecular components that produce mechanical movements when exposed to specific external stimuli. Naturally occurring biological machines include multi-protein complexes like kinesins and ribosomes, which carry out vital processes such as DNA replication and adenosine triphosphate synthesis. [2]

According to Phys.org Chemistry, controlling self-assembly at the molecular scale moves research closer to replicating natural multi-protein functions. The precise assembly of synthetic structures could lead to future applications in chemical and material science. [1][2]